Dehydroepiandrosterone (DHEA): Hypes or Hopes.Drugs, 74, 1195-1207.

[i] Schauss A. G. (1991). We use this ever-evolving list to screen the products we carry, so you dont have to worry. Currently, there are thousands of artificial chemicals and additives that are allowed to be added to our food and more being approved every day. 2010; 4(4): 1003-1007, [iii] Teff, K. L., Elliott, S. S., Tschp, M., Kieffer, T. J., Rader, D., Heiman, M., Townsend, R. R., Keim, N. L., D'Alessio, D., & Havel, P. J. (2018).

Retrieved January 14, 2021 from https://www.usnews.com/news/us/articles/2016-05-20/states-ban-kratom-supplement-over-abuse-worries, [iii] Kraoma. Available at https://www.federalregister.gov/documents/2019/08/01/2019-16374/listing-of-color-additives-exempt-from-certification-soy-leghemoglobin, [ii] Fraser, R.Z., Shitut, M., Agrawal, P., Mendes, O., Klapholz, S. (2018). doi:10.1098/rsif.2009.0252.focus. https://www.foodnavigator-usa.com/Article/2019/05/13/Tate-Lyle-talks-allulose-The-first-two-things-consumers-look-for-on-the-Nutrition-Facts-panel-now-are-calories-and-sugar#, https://www.nytimes.com/1993/03/26/nyregion/imported-bitter-apricot-pits-recalled-as-cyanide-hazard.html?sec=health, https://cspinet.org/sites/default/files/attachment/food-dyes-rainbow-of-risks.pdf, https://oehha.ca.gov/risk-assessment/press-release/report-links-synthetic-food-dyes-hyperactivity-and-other, https://www.cspinet.org/sites/default/files/attachment/9th_report_letter.pdf, https://doi.org/10.1007/s10086-018-1766-0, https://www.popsci.com/history-flavors-us-pictorial/, https://doi.org/10.1016/j.fct.2008.11.011, https://doi.org/10.1161/CIRCULATIONAHA.107.689935, https://doi.org/10.1161/CIRCULATIONAHA.107.716159, https://pdfs.semanticscholar.org/6465/68d84a55f1ba03530cd577fd7c82b47c1e23.pdf, https://www.researchgate.net/publication/225029050_Aspartame_induces_lymphomas_and_leukaemias_in_rats, https://doi.org/10.1016/j.ntt.2014.02.001, https://doi.org/10.1016/j.fct.2017.04.045, https://doi.org/10.1016/j.fct.2019.110692, https://doi.org/10.1371/journal.pone.0162198, http://www.lightenyourtoxicload.com/wp-content/uploads/2014/07/Dr-Walton-survey-of-aspartame-studies.pdf, https://www.fda.gov/food/food-additives-petitions/questions-answers-about-4-mei, https://monographs.iarc.fr/wp-content/uploads/2018/06/mono101-015.pdf, https://www.ewg.org/foodscores/ingredients/16660CARAMELCOLOR, https://www.ncbi.nlm.nih.gov/books/NBK548355/, https://www.ncbi.nlm.nih.gov/books/NBK216051/, https://www.hsph.harvard.edu/nutritionsource/what-should-you-eat/fats-and-cholesterol/types-of-fat/transfats/, https://doi.org/10.1016/j.toxlet.2017.05.020, https://doi.org/10.1016/j.foodchem.2012.01.058, https://www.omicsonline.org/open-access/progress-in-synthesis-of-monoglycerides-for-use-in-food-andpharmaceuticals-2472-0542-1000128.pdf, https://www.ncbi.nlm.nih.gov/books/NBK548370/, https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=dhea, https://www.stlukes-stl.com/health-content/medicine/33/000299.htm#:~:text=High%20doses%20of%20DHEA%20may,liver%20disease%20should%20avoid%20DHEA, https://www.fda.gov/food/dietary-supplements, https://www.ncbi.nlm.nih.gov/books/NBK153666/, https://doi.org/10.1002/j.1875-9114.1996.tb03655.x, https://www.cargill.com/food-beverage/na/eversweet-faqs, https://www.ecowatch.com/eversweet-non-gmo-certification-2603754941.html, https://doi.org/10.1177%2F1091581815602252, https://www.deadiversion.usdoj.gov/drug_chem_info/hgh.pdf, https://www.accessdata.fda.gov/cms_ia/importalert_204.html, https://www.bbc.co.uk/bitesize/guides/z7rswty/revision/1, https://doi.org/10.1016/j.foodchem.2020.127000, https://www.dea.gov/sites/default/files/2020-06/Kratom-2020_0.pdf, https://www.usnews.com/news/us/articles/2016-05-20/states-ban-kratom-supplement-over-abuse-worries, https://kraoma.com/kratom-legality-united-states/, https://www.fda.gov/news-events/press-announcements/fda-oversees-destruction-and-recall-kratom-products-and-reiterates-its-concerns-risks-associated, https://www.fda.gov/food/cfsan-constituent-updates/recent-fda-action-dietary-supplements-which-product-labeling-lists-methylsynephrine-dietary, https://www.ewg.org/release/analysis-finds-hormone-disruptor-used-cosmetics-nearly-50-different-foods, http://apps.who.int/iris/bitstream/handle/10665/43592/WHO_TRS_940_eng.pdf?sequence=1, http://www.nuclmed.gr/wp/wp-content/uploads/2017/04/10.pdf, https://oehha.ca.gov/proposition-65/proposition-65-list, https://ntp.niehs.nih.gov/ntp/roc/content/profiles/butylatedhydroxyanisole.pdf, https://www.ewg.org/research/ewg-s-dirty-dozen-guide-food-additives/generally-recognized-as-safe-but-is-it, https://www.ewg.org/research/ewg-s-dirty-dozen-guide-food-additives, https://journals.sagepub.com/doi/10.1080/10915810290096522#articleCitationDownloadContainer, https://www.ncbi.nlm.nih.gov/pubmed/?term=McCann+D+(2007).+Food+additives+and+hyperactive+behaviour+in+3-year-old+and+8%2F9-year-old+children+in+the+community%3A+a+randomised%2C+double-blinded%2C+placebo+controlled+trial.+Lancet%2C+370%2C+1560-156, http://www.journalrepository.org/media/journals/EJNFS_30/2014/Jul/Sande442014EJNFS10405_1.pdf, https://cspinet.org/eating-healthy/chemical-cuisine#propyleneglycol, https://www.ncbi.nlm.nih.gov/pubmed/9537614, http://www.efsa.europa.eu/en/press/news/151118, https://academic.oup.com/femsre/article/25/1/69/606255, https://www.federalregister.gov/documents/2019/08/01/2019-16374/listing-of-color-additives-exempt-from-certification-soy-leghemoglobin, https://www.gmoscience.org/rat-feeding-studies-suggest-the-impossible-burger-may-not-be-safe-to-eat/, http://lpi.oregonstate.edu/mic/vitamins/vitamin-E, http://www.chiro.org/nutrition/FULL/Natural_vs_Synthetic_Vitamin_E.shtml, https://ods.od.nih.gov/factsheets/VitaminE-HealthProfessional/, https://www.usp.org/frequently-asked-questions/talc-monograph, https://www.fda.gov/news-events/fda-brief/fda-brief-fda-releases-final-report-talc-containing-cosmetic-products-tested-asbestos, https://www.cancer.org/cancer/cancer-causes/asbestos.html, https://www.foodprocessing.com.au/content/food-design-research/news/talc-use-in-food-processing-a-health-hazard-say-researchers-859641872, https://doi.org/10.1016/j.urology.2016.12.066, https://doi.org/10.1186/s12951-018-0376-8, Read More About Things We Won't Carry and Why. Under the conditions of intended use new developments in the FEMA GRAS program and the safety assessment of flavor ingredients. We will never carry any supplement that contains iron oxide either as a color additive or as a source of iron. There have been sporadic reports of people developing hepatotoxicity (liver toxicity), in some cases requiring a liver transplant, after the ingestion of chaparral.

Please see "Artificial colors"for more information. Side effects associated with the use of HGH include edema, carpal tunnel syndrome, joint pain, muscle pain, fatigue, and elevated cholesterol and glucose. The enzymes used may also be produced from genetically modified microbes. Am J Clin Nutr, 108(3), 485-491. https://doi.org/10.1093/ajcn/nqy152, [xii] Abu-Taweel, G.M., Zyadah, M.A., Ajarem, J.S., Ahmad, M. (2014).

Synthetic Vitamin E. Nutrition Science News. PEG, most commonly derived from petroleum, can be contaminated with trace amounts of 1,4-dioxane, a human carcinogen. Analysis finds hormone disruptor used in cosmetics in nearly 50 different foods.

[ii] Kharrazian, D. (2010). [i] Oxidation and reduction - Redox, rusting and iron - (CCEA) - GCSE Chemistry (Single Science) Revision - CCEA - BBC Bitesize. Toxicological aspects of interesterified fat: Brain damages in rats. DHEA is a hormone produced chiefly by the adrenal glands that has many regulatory functions in the body. Please see "AgaveGrandmothered & Limited" for more information. In LiverTox: Clinical and research information on drug-induced liver injury [internet]. Despite significant public opposition and uncertainty about the safety of GM animals, the FDA approved GM AquAdvantage salmon for sale in the United States. [ii] Wilbur, S, Jones, D., Risher JF, Crawford, J., Tencza, B., Llados, F., Lockwood, L. (2012). For more details see the DHEA section above. [i] n.a.

In LiverTox: Clinical and research information on drug-induced liver injury [internet]. Import alert 66- 7 one: detention without physical examination of human growth hormone (HGH), also known as somatropin. (2017). (2018, February 21). Comfrey contains pyrrolizidine alkaloids that when taken internally are toxic and can cause severe liver injury. [i] Jiang, S., Xiao, W., Zhu, X., Yang, P., Zheng, Z., Lu, S., Liu, J. While an injectable form is approved by prescription for a limited number of diseases; it is often touted as an anti-aging therapy and/or used to enhance sports performance. It is for these reasons that we dont sell pregnenolone and feel that self-supplementation with pregnenolone, and self-diagnosis of low pregnenolone levels, is inappropriate and potentially dangerous. Apricot kernels naturally contain the poison cyanide. Food additives and hyperactive behavior in 3-year-old and 8/9-year-old children in the community: a randomized, double-blinded, placebo-controlled trial. https://www.dea.gov/sites/default/files/2020-06/Kratom-2020_0.pdf, [ii] Brown.

(n.d.). Drug testing and analysis, 9 (1), 135-142. https://doi.org/10.1002/dta.1976. Retrieved from: https://oehha.ca.gov/risk-assessment/press-release/report-links-synthetic-food-dyes-hyperactivity-and-other, [i] Schlagheck, T.G., Riccardi, K.A., Zorich, N.L., Torri, S.A., Dugan, L.D., Peters, J.C. (1997). [iii] Liontiris, M.I., Mazokopakis, E.E.

The CLA that is found in supplements is made via the partial hydrogenation of sunflower oil and is identical to CLA found naturally occurring in grass-fed dairy products that has demonstrated health supportive benefits. For example, an excess of DHEA can promote tumor growth, encourage liver toxicity, and disrupt hormone balance, which can produce a wide range of symptoms including facial hair on women and breast swelling in men. Food and Chemical Toxicology, 132, 110692. https://doi.org/10.1016/j.fct.2019.110692, [xvii] Mandrioli, D., Kearns, C.E., Bero, L.A. (2016).

(2019). Parabens have been shown to act as weak xenoestrogens and may cause hormone disruption. Reg. Until diatomaceous earth is recognized as a legal supplement by the FDA we will not carry it. Please see "Comfrey (Symphytum officinale), internal sources"for more information. Please see "Preservatives" for more information.

Retrieved January 14, 2021 from https://kraoma.com/kratom-legality-united-states/, [iv] U.S. Food and Drug Administration. (June 25, 2019). Please see "White kidney bean" for more information. Cognitive and biochemical effects of monosodium glutamate and aspartame, administered individually and in combination in male albino mice. The process of making artificial colors is extremely hazardous and can result in very dangerous chemicals in the final product. While we favor products that do not use parabens and have encouraged any manufacturers that do use parabens in their products to change their formulations, it may not be possible to change the preservative in some products due to molecular interactions. Available at: https://ods.od.nih.gov/factsheets/VitaminE-HealthProfessional/, [iv] Burton GW, Traber MG, Acuff RV, et al. Food Navigator USA website.

Critical review of the safety assessment of titanium dioxide additives in food. Obesity, 16:1894-1900. [i] Listing of Color Additives Exempt from Certification; Soy Leghemoglobin; 84 Fed. Unlike other carbohydrates, fructose does not suppress the production of the hunger hormone ghrelin but still stimulates reward in the brain which leads to excessive consumption.

Propylene glycol: the safe diluent that continues to cause harm. Because manufacturers dont have to specify on the label which class of caramel coloring they use, we ensure that any manufacturer using caramel color is using class I, the only caramel color that does not contain added sulfite or ammonia and is the only caramel color produced in normal cooking processes. Animal studies have found that nordihydroguaiaretic acid (NDGA), a major component of chaparral, can cause toxicity and kidney damage. (2011). Journal of nanobiotechnology,16(1), 51. https://doi.org/10.1186/s12951-018-0376-8, [iii] Bettini, S., Boutet-Robinet, E., Cartier, C., Comra, C., Gaultier, E., Dupuy, J., Houdeau, E. (2017). Tate & Lyle: The first two things consumers look for on the Nutrition Facts Panel now are calories and sugar. Washington, DC: National Academy Press. Food Chemistry, 133(3), 678-682. https://doi.org/10.1016/j.foodchem.2012.01.058, [vii] Vorhees, C.V., Butcher, R.E., Wootten, V., Brunner, R.L. J R Soc Interface, 7(suppl 1), s119-s129. The presence of iron oxide nanoparticles in the food pigment E172. DOI:10.1093/jn/127.8.1646S, [ii] Jacobson, M. F. (2004, October 21).

Ethoxylated mono- and diglyceridesGrandmothered & Limited, Fish oil derived from GM salmon or any other GM fish/seafood, Please see "Chemically modified fats" for more information, Genetically modified (GM) salmon or any other GM animal/seafood products, GuaranaGrandmothered & Limited Ingredient, Kola Nut (Cola acuminata/Cola nitada)Grandmothered & Limited. The list below does not list every single ingredient that we do not carry. (n.d.). Determination of pyrrolizidine alkaloids in commercial comfrey products (Symphytum sp.). The Journal of clinical endocrinology and metabolism,89(6), 29632972. Natural vs. (2006). to your preferred store.

[i] The Proposition 65 List.

Retrieved from https://cspinet.org/eating-healthy/chemical-cuisine#propyleneglycol, [ix] Burton GW, Traber MG, Acuff RV, et al. Retrieved from https://cspinet.org/sites/default/files/attachment/food-dyes-rainbow-of-risks.pdf, [ii] Food Dyes - Center for Science in the Public Interest.

Associations between nonnutritive sweetener intake and metabolic syndrome in adults. We've put together a growing list of the most problematic supplement ingredients, many of which are still commonly found in supplements at other retailersand onlinebut never here. Talc poses the greatest danger to workers exposed to it, but consumer exposure to talc may also increase the risk of developing cancer.

(2018, July 12). DOI:10.1097/00001648-199403000-00012, [viii] Abd El-Samad, A.A. (2010). Lactylated esters of mono- and diglycerides, Mono- and diglyceridesGrandmothered & Limited.

Scientific opinion on the re-evaluation of mono- and di-glycerides of fatty acids (E471) as food additives. See Chemically modified fats" for more information. Retrieved from https://www.researchgate.net/publication/225029050_Aspartame_induces_lymphomas_and_leukaemias_in_rats, [x] Soffritti, M., Belpoggi, F., Degli Esposti, D., Lambertinin, L., Tibaldi, E., Rigano, A. These frankenfish pose a great risk to the environment and wild fish populations, should they escape into the wild. Please see "Artificial fats" for more information.

These unnatural fats can cause extremely uncomfortable gastrointestinal issues. Updated May 2015. http://lpi.oregonstate.edu/mic/vitamins/vitamin-E, [ii] Challem J. Please see "Parabens" for more information. 37573 (Aug 1, 2019) (to be codified at 21 CFR 73). Consumption of artificial sweetener- and sugar-containing soda and risk of lymphoma and leukemia in men and women.

Naturopaths and Medical Doctors do not recommend using testosterone cream unless blood levels have been checked and proven low.

[iv] Institute of Medicine Food and Nutrition Board. (Nov 18, 2015) Ethoxyquin: EFSA safety assessment inconclusive. Behavioral and reproductive effects of chronic developmental exposure to brominated vegetable oil in rats.

Retrieved November 16, 2020, from https://www.cargill.com/food-beverage/na/eversweet-faqs, [iii] Roseboro, K. (2019, December 18). Propylene glycol in large oral doses is associated with central nervous system depression, lactic acidosis, seizures, and red blood cell destruction (hemolysis).

Part Fibre Toxicol, 12, 26. doi:10.1186/s12989-015-0101-9, [ii] Winkler, H. C., Notter, T., Meyer, U., & Naegeli, H. (2018). Nutrients, 11, 46. doi:10.3390/nu11020466. Please see "Artificial flavors"for more information. (n.d.). FDA oversees destruction and recall of kratom products; and reiterates its concern on risks assoiciated with this opioid [Press release]. (1994). (2015). US Drug Enforcement Administration. https://doi.org/10.1210/jc.2003-031855, [vi] Maldonado-Guevara, B.I., Mart del Campo, S.T., Cardador-Mart ez, A. Egyp J Histol, 33(3), 419-430. http://apps.who.int/iris/bitstream/handle/10665/43592/WHO_TRS_940_eng.pdf?sequence=1. Just want to see prices and content for your local store? EWG's food scores just took the work out of grocery shopping for me! The use of HGH should be regulated by a trained doctor for specific medical conditions.

Kratom legality 2021: map, legal status, and ban updates. Internal comfrey use has been associated with liver cancer in animals.

Critical review of the safety assessment of titanium dioxide additives in food. https://www.gmoscience.org/rat-feeding-studies-suggest-the-impossible-burger-may-not-be-safe-to-eat/, [iv] Jin, Y., He, X., Andoh-Kumi,K., Fraser, R.Z., Lu, M., Goodman, R.E. Chaparral-associated hepatotoxicity. Arch Intern Med, 157(8), 913-919. United States. Unlike other retailers, when it comes to quality vitamins and supplements, we dont just talk the talkwe research, take a fine-tooth comb to, and deliberate over each ingredient allowed in the supplements we carry on our shelves. New York, NY: Springer. Dietary intake and the development of the metabolic syndrome. Review on D-allulose: In vivo metabolism, catalytic mechanism, engineering strain construction, bio-production technology.

Chemically modified fats are sometimes used by supplement manufacturers as a filler or to aid in processing. The sweetener agave is composed of 75% to 85% free fructose.

Sign-up for {N}power to get exclusive discounts, newsletters, members-only features, and more! Please see "Human growth hormone (HGH)"for more information. Please see "Apricot kernels" for more information. In the 1950s, new requirements for food chemicals were imposed, but because there were so many flavors and flavor additives already in use at that time, the FDA simply exempted them from testing requirements, essentially grandfathering them in as safe. We've allowed the least harmful preservatives in a limited number of products because there are no good natural alternatives. M. (May 6, 2016). Artificial sweetener consumption and urinary tract tumors in Cordoba, Argentina. Retrieved from: https://www.ncbi.nlm.nih.gov/books/NBK548370/.

Nephrotoxicity and neurotoxicity in humans from organogermanium compounds and germanium dioxide. (2021, Apr). GMO Science. 368 S Broadway (2004). There are three glycols occasionally added to supplements that Natural Grocers does not allow: Polyethylene glycol (PEG), propylene glycol, and propylene glycol alginate (alginic acid from seaweed esterified with propylene glycol). Progress in synthesis of monoglycerides for use in pharmaceuticals. Because vanillin is made from genetically modified yeasts and is not natural, we do not carry products that contain it. Retrieved January 26, 2021, from https://www.usp.org/frequently-asked-questions/talc-monograph, [ii] Richards, M. (2020, March 9).

Please see 'Chemically modified fats' for more information.

Aspartame induces lymphomas and leukaemias in rats.

Front Bioeng Biotechnol, 8, 26. doi:10.3389/fbioe.2020.00026, [ii] Watson, E. (2009, May 13).

Please see "Artificial sweeteners"for more information.

Because of such potential problems, the use of high dose iodine therapy should be supervised by a doctor. Please see "Chemically modified fats"for more information. Artificially sweetened beverage use and long-term weight gain. [i] Hasenhuettl, G.L., Hartel, R.W. Pharmaceutical/food grade titanium dioxide particles are absorbed into the bloodstream of human volunteers.

HGH is a hormone released by the pituitary gland that is involved in growth and repair of organs and tissues.

Updated Nov 3, 2016. Sign-up for {N}power to get exclusive discounts, newsletters, members-only features, and more! AquAdvantage salmon are genetically modified to produce growth hormone continually, causing the fish to grow much larger and faster than conventionally-raised farmed salmon. Caramel colors II, III, and IV are created by heat treating carbohydrates with a sulfite-containing compound, an ammonium-containing compound, or both. The inexorable rise of synthetic flavor: a pictorial history. (2018).

http://www.efsa.europa.eu/en/press/news/151118, [xii] Bucheli-Witschel M, Egli T. Environmental fate and microbial degradation of aminopolycarboxylic acids.

(2011). https://doi.org/10.1111/cea.12760, [iv] Glover, M. L., & Reed, M. D. (1996). (2012). Many preservatives have dubious safety profiles. (2014, November 12). For those who wish to employ alternative treatments we encourage them to work closely with their health practitioner.

[i] European Food Safety Authority.

We never take lightly the fact that youve trusted us with your healthand thats why all the supplements we carrygothrough a rigorous screening process by ourquality standards experts. (2014).

Nanoparticles, human health hazard and regulation. [i] Drug Enforcement Administration. [i] (2016, March 31). [xvii] [xviii], [i] Fowler, S.P., Williams, K., Resendez, R.G., Hunt, K.J., Hazuda, H.P., Stern, M.P. FDA certified color additives are generally identified by a letter prefix, the color, and then a number (e.g., FD&C Yellow #5).

There is a real need for certain liquid supplements to have some preservatives due to the serious potential for mold or bacteria to develop without them. It is for these reasons that we do not sell DHEA and feel that self-supplementation with DHEA, and self-diagnosis of low DHEA levels, is inappropriate and potentially dangerous. 1998 Apr;67(4):669-684. https://www.ncbi.nlm.nih.gov/pubmed/9537614, [i] FAQs: Modernization of the USP Talc Monograph. F.A., Koller, D., Thompson, R, P.H., Lomer, M.C., Powell, J.J. (2015).

There is always one constant within the changes made to the list, our commitment to quality.

Retrieved January 26, 2021, from https://www.cancer.org/cancer/cancer-causes/asbestos.html, [iv] (2015, September 30). Production process effect on Mexican agave syrups quality: a preliminary study. U.S. News. J Pharm Sci, 83(5), 649-653.

When fructose is absorbed, it goes directly to the liver where it is converted into fat (aka triglycerides).

Read more about grandmothered and limited ingredients. They increase the manufacturers bottom line at the expense of consumer health. Please see Genetically modified (GM) salmon or any other GM animal/seafood product" for more information. Popular Science website. (1983). Res Nurs Health, 37(3), 185-193. doi:10.1002/nur.21595, [xiv] Bian, X., Tu, P., Chi, L., Gao, B., Ru, H., Lu, K. (2017). (n.d.). Retrieved June 20, 2019, from https://www.hsph.harvard.edu/nutritionsource/what-should-you-eat/fats-and-cholesterol/types-of-fat/transfats/, [ii] Afonso, M.S., Lavrado, M.S., Koike, M.K., Cintra, D.E., Ferreira, F.D., Nunes, V.S.,Lottenberg, A.M. (2016).

[i] https://www.nytimes.com/1993/03/26/nyregion/imported-bitter-apricot-pits-recalled-as-cyanide-hazard.html?sec=health), [i] Food Dyes - Center for Science in the Public Interest. In numerous studies, synthetic vitamin E supplements have been shown to be inferior to natural vitamin E supplements in bioavailability, resulting in as little as half the plasma and tissue levels of vitamin E obtained by an equal weight of natural vitamin E. Talc is sometimes used in supplements to prevent ingredients from clumping and sticking to machinery during the formation of tablets.

Vitamin E Fact Sheet for Health Professionals. Food and chemical Toxicology, 107, 530-539. https://doi.org/10.1016/j.fct.2017.04.045, [xv] Chi, L., Bian, X., Gao, B., Tu, P., Lai, Y., Ru, H., Lu, K. (2018).

Research suggests that chronic ingestion of titanium dioxide induces low-grade inflammation of the colon and alters gut homeostasis in ways that may contribute to the development of autoimmune conditions, and of chronic inflammatory gastrointestinal issues such as Inflammatory Bowel Disease and colon cancer. Not only do we feel this ingredient poses risks to those who might take it, but we carefully screen our products to ensure that they do not contain pharmaceutical drugs masquerading as dietary supplements and we do not condone the illegal use of this ingredient in any dietary supplement. Int J Toxicol, 34(6), 543-550. https://doi.org/10.1177%2F1091581815602252. Food Chem, 327, 127000. https://doi.org/10.1016/j.foodchem.2020.127000, [iii] Sadeghi, L., Babadi,V.Y., Espanani, H.R. https://www.fda.gov/news-events/press-announcements/fda-oversees-destruction-and-recall-kratom-products-and-reiterates-its-concerns-risks-associated.